Assorted medicinal mushrooms and supplements with a dropper bottle.

What should I know about Harm Reduction?

While some people choose to micro-dose while on medication, the effects can vary and safety is always our top priority.

  • Psilocybin is a psychoactive compound that may interact with certain medications.
  • SSRIs and SNRIs may dull or block the effects of psilocybin due to serotonin receptor competition.
  • Other medications – especially those that impact the brain, mood, or serotonin, may also ause unpredictable interactions.

Because each person’s body is different, we strongly encourage you to speak with a qualified healthcare provider before microdosing, especially if you are taking:

  • Antidepressants (SSRIs, SNRIs, MAOIs)
  • Mood stabilizers
  • Anti-anxiety or antipsychotic medications
  • Seizure medications
  • Blood pressure or heart medications

What many people choose to do:

  • Some people wait until they’ve tapered off certain medications (under medical supervision) before beginning micro-dosing.
  • Others experiment gently, beginning with low doses and noting any unusual effects. 

Psilocybin’s Impact on Brain Connectivity in Body Dysmorphic Disorder https://www.shroomer.com/psilocybin-body-dysmorphic-disorder/